3-(Trifluoromethy)pyridine-2-carboxylic acid - Names and Identifiers
3-(Trifluoromethy)pyridine-2-carboxylic acid - Physico-chemical Properties
Molecular Formula | C7H4F3NO2
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Molar Mass | 191.11 |
Density | 1.484g/cm3 |
Melting Point | 125-130°C |
Boling Point | 274.4°C at 760 mmHg |
Flash Point | 119.7°C |
Solubility | DMSO (Slightly), Methanol (Slightly) |
Vapor Presure | 0.00264mmHg at 25°C |
Appearance | Solid |
Color | Off-White |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Refractive Index | 1.475 |
MDL | MFCD07375386 |
3-(Trifluoromethy)pyridine-2-carboxylic acid - Risk and Safety
Risk Codes | R25 - Toxic if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
|
UN IDs | 2811 |
WGK Germany | 3 |
Hazard Class | IRRITANT |
Packing Group | Ⅲ |
3-(Trifluoromethy)pyridine-2-carboxylic acid - Introduction
3-(Trifluoromethyl)pyridine-2-carboxylic acid, the chemical formula is C≡H≡F≡NO₂.
Nature:
3-(Trifluoromethyl)pyridine-2-carboxylic acid is a colorless crystalline solid with special chemical properties. It has a melting point of about 122-126 degrees Celsius and a boiling point of 328 degrees Celsius. It is not volatile at room temperature.
Use:
3-(Trifluoromethyl)pyridine-2-carboxylic acid has a wide range of applications in the field of organic synthesis. It is often used as a catalyst, intermediate and raw material. It can participate in a variety of organic reactions, such as nucleophilic substitution reactions, addition reactions and the synthesis of carboxylic acid derivatives.
Preparation Method:
3-(Trifluoromethyl)pyridine-2-carboxylic acid has many synthetic methods, one of which is obtained by the reaction of 3-trifluoromethylpyridine and carbon dioxide. The specific step is that 3-trifluoromethylpyridine and carbon dioxide are reacted under heating conditions to generate 3-(Trifluoromethyl)pyridine-2-carboxylic acid. The synthetic methods generally require the use of catalysts, solvents and appropriate reaction conditions.
Safety Information:
3-(Trifluoromethyl)pyridine-2-carboxylic acid is generally relatively safe under proper use, but the following matters still need to be paid attention:
1. When handling the compound, care should be taken to avoid contact with skin, eyes or inhalation of its dust. Appropriate personal protective equipment such as gloves, glasses and masks should be worn.
2. should be stored in a cool and dry place, away from fire and oxidant, so as not to cause fire or explosion.
3. The compound may have a certain risk to the environment and should be handled and disposed of in accordance with relevant regulations.
Please note that the information provided above is for informational purposes only, reference should be made to the relevant literature on chemicals and chemical safety manuals, and the relevant environmental, health and safety guidelines should be strictly followed during the experiment.
Last Update:2024-04-10 22:29:15